|Ποσότητα παραγγελίας min:||100g|
|Συσκευασία λεπτομέρειες:||Τσάντα φύλλων αλουμινίου|
|Χρόνος παράδοσης:||3-7days μετά από τη λαμβανόμενη πληρωμή|
|Όροι πληρωμής:||T/T, Western Union, MoneyGram|
|Δυνατότητα προσφοράς:||5000Kg το μήνα|
|CAS:||58-18-4||Χρώμα ή εμφάνιση:||Άσπρη κρυστάλλινη σκόνη|
|Χρήση προϊόντων:||Προσθέστε το μυ||Προδιαγραφή συσκευασίας:||Τσάντα φύλλων αλουμινίου αργιλίου ή κασσίτερος 25 kg/barrel αργιλίου|
|Πρότυπα εκτέλεσης:||USP42||Αγνότητα προϊόντων:||99%|
|Το επίπεδο προϊόντων:||Φαρμακευτικός βαθμός||Μοριακός τύπος:||C20H30O2|
C20H30O2 ακατέργαστη σκόνη στεροειδών,
Τα ακατέργαστα στεροειδή κονιοποιούν 17 Methyltestosterone
C20H30O2 Hormone Raw Steroid Powders 17 Methyltestosterone CAS 58-18-4
Product Name: 17-Methyltestosterone,Methyltestosterone
Usage :pharmaceutical raw materials, the hormone
Methyltestosterone is or has been used in the treatment of delayed puberty, hypogonadism, cryptorchidism, and erectile dysfunction in males, and in low doses to treat menopausal symptoms (specifically forosteoporosis, hot flashes, and to increase libido and energy), postpartum breast pain and engorgement, andbreast cancer in women.
Methyltestosterone is used for physique- or performance-enhancing purposes by competitive athletes,bodybuilders, and powerlifters, although it is not commonly used relative to other AAS for such purposes.
The dosages of methyltestosterone used are 10 to 50 mg/day in men for common medical uses and physique- and performance-enhancing purposes and 2.5 mg/day in women for menopausal symptoms.Higher dosages of as much as 200 mg/day have been used to treat women with inoperable breast cancer that has failed to respond to other therapies.
Methyltestosterone should be used with caution in women and children, as it can cause irreversiblevirilization. Due to its estrogenicity, methyltestosterone can also accelerate epiphyseal closure and thereby produce short stature in children and adolescents.It can worsen symptoms in men with benign prostatic hyperplasia. Methyltestosterone should not be used in men with prostate cancer, as androgens can accelerate tumor progression. The drug should be used with caution in patients with pre-existinghepatotoxicity, due to its own potential for hepatotoxicity.
Adverse effects of methyltestosterone include androgenic side effects like oily skin, acne, seborrhea, increased facial/body hairgrowth, scalp hair loss, increased aggressiveness and sex drive, and spontaneous erections, as well as estrogenic side effects like gynecomastia, fluid retention, and edema. In women, methyltestosterone can cause partially irreversible virilization, for instance voice deepening, hirsutism,clitoromegaly, breast atrophy, and muscle hypertrophy, as well as menstrual disturbances and reversibleinfertility. In men, the drug may also cause hypogonadism, testicular atrophy, and reversible infertility at sufficiently high dosages.
Methyltestosterone can sometimes cause hepatotoxicity, for instance elevated liver enzymes, cholestatic jaundice, peliosis hepatis, hepatomas, and hepatocellular carcinoma, with extended use. It can also have adverse effects on the cardiovascular system. AAS like methyltestosterone stimulate erythropoiesis (red blood cell production) and increase hematocrit levels and at high dosages can cause polycythemia(overproduction of red blood cells), which can greatly increase the risk of thrombic events such as embolismand stroke. With long-term treatment, AAS can increase the risk of benign prostatic hyperplasia and prostate cancer. Violent and even homicidal behavior, hypomania/mania, depression, suicidality, delusions, andpsychosis have all been associated with very high dosages of AAS.
Aromatase inhibitors can be used to reduce or prevent the estrogenic effects of methyltestosterone and 5α-reductase inhibitors can be used to prevent its potentiation in so-called "androgenic" tissues and thereby improve its ratio of anabolic to androgenic activity and reduce its rate of androgenic side effects.Antiandrogens like bicalutamide and cyproterone acetate can block both the anabolic and androgenic effects of AAS like methyltestosterone.
As an AAS, methyltestosterone is an agonist of the androgen receptor (AR), similarly to androgens liketestosterone and dihydrotestosterone (DHT). It is a substrate for 5α-reductase like testosterone, and so is potentiated analogously in so-called "androgenic" tissues like the skin, hair follicles, and prostate gland viatransformation into the more potent AR agonist mestanolone (17α-methyl-DHT). As such, methyltestosterone has a relatively low ratio of anabolic to androgenic activity, with a similar ratio to that of testosterone (close to 1:1), and this makes it among the most androgenic AAS. Due to efficientaromatization into the potent and metabolically resistant estrogen methylestradiol (17α-methylestradiol), methyltestosterone has relatively high estrogenicity and hence potential for estrogenicside effects such asgynecomastia and fluid retention. The drug possesses negligible progestogenic activity.
Due to its combined disadvantages of a relatively poor ratio of anabolic to androgenic activity, unusually high estrogenicity, and the potential for hepatotoxicity, methyltestosterone has not been used as commonly as many other AAS either in medicine or for physique- or performance-enhancing purposes.
Because of its C17α methyl group, methyltestosterone has dramatically improved oral bioavailability andmetabolic stability relative to testosterone, and for this reason, unlike testosterone, is orally active. The oral bioavailability of methyltestosterone is about 70%, and its terminal half-life is approximately 3 hours (range 2.5–3.5 hours), with a duration of action of 1 to 3 days. Its duration is described as relatively short among AAS. Methyltestosterone can also be taken buccally or sublingually, and this is said to approximately double its bioavailability. The drug is highly protein-bound, by approximately 98%, including to sex hormone-binding globulin (SHBG) with about 25% of the affinity of testosterone. It is excreted 90% in the urine asconjugates and metabolites, and 6% in feces.
|Test Items||Specification||Test Results|
|Characteristics||White to almost white crystalline powder||Conform|
|Specific optical rotation||+79°～ +85°||+82.5°|
|Loss on drying||≤2.0%||1.1%|
|Residual solvents(GC)||Acetone ≤100ppm||Pass|
|Conclusion||This batch is complies with USP31|
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we accept Bank Transfer, Western Union and Money Gram
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location.For small order,please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.For mass order,please allow 5-8 days by Air, 20-35 days by Sea.
Q7:Do you have any resend policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q8:Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
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